Ensaios Clínicos (somente visualização)

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9251
RBR-1088scr6
Effect of Creatine with Walking on Peripheral Arterial Disease
Influence of Creatine Supplementation Associated with Walking Exercise on Gait Performance, Muscular Aspects, and Biomarkers in Patients with Peripheral Arterial Disease (PAD) with Intermittent Claudication: A Randomized Double-Blind Clinical Trial
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Recruiting
Intervention
n/a, randomized-controlled, double-blind
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2026-05-26
2025-07-23
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Universidade Estadual Paulista "Júlio de Mesquita Filho"- UNESP
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Adult patients with age greater than eighteen years; diagnosis of symptomatic peripheral arterial disease (PAD); presence of intermittent claudication in one or both lower limbs; peripheral arterial disease documented by absence or reduction of distal pulses on palpation in the affected limb; ankle-brachial index less than zero point ninety; clinical classification compatible with peripheral arterial disease according to the severity criteria of the Rutherford and/or Fontaine classifications; ability to understand and follow the study instructions; agreement to participate in the study by signing the Informed Consent Form.
Diagnosis of dementia; critical limb ischemia; presence of foot ulcers; amputation; residence in a nursing home; inability to walk on a treadmill or to perform exercise three times per week; failure to complete the initial exercise sessions; history of surgery or myocardial infarction within the last three months; planned surgery within the next year; current participation in other clinical trials; medical contraindication to perform physical exercise; limitation to walk due to a cause not related to peripheral arterial disease (PAD); poorly controlled hypertension; previous kidney disease with creatinine clearance less than or equal to thirty milliliters per minute per one point seventy-three square meters.
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2026-06-01 05:24:02